INDOMETHACIN AND COGNITIVE FUNCTION IN HEALTHY ELDERLY VOLUNTEERS

被引：40

作者：

BRUCEJONES, PNE

CROME, P

KALRA, L

机构：

[1] Orpington Clinical Age Research Unit, Kings College School of Medicine and Dentistry, Orpington Hospital, Kent

来源：

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY | 1994年 / 38卷 / 01期

关键词：

INDOMETHACIN; COGNITIVE FUNCTION;

D O I：

10.1111/j.1365-2125.1994.tb04320.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

1 Cognitive function was studied after single and multiple doses of indomethacin (I) and matched placebo (P) in 20 healthy elderly volunteers using a double-blind crossover design. 2 Arousal, attention, integration, coordination, memory and mood were investigated using a battery of psychomotor tests and the Hospital Anxiety and Depression Scale. Assessments were performed before and after the first and last doses of a 7 day course of medication.

引用

页码：45 / 51

页数：7

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