EVIDENCE FOR CROSS-PATHWAY REGULATION OF METABOLIC GENE-EXPRESSION IN PLANTS

被引：72

作者：

GUYER, D ^{[1
]}

PATTON, D ^{[1
]}

WARD, E ^{[1
]}

机构：

[1] CIBA AGR BIOTECHNOL,RES TRIANGLE PK,NC 27709

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1995年 / 92卷 / 11期

关键词：

D O I：

10.1073/pnas.92.11.4997

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

In Arabidopsis thaliana, blocking histidine biosynthesis with a specific inhibitor of imidazoleglycerol-phosphate dehydratase caused increased expression of eight genes involved in the biosynthesis of aromatic amino acids, histidine, lysine, and purines. A decrease in expression of glutamine synthetase was also observed. Addition of histidine eliminated the gene-regulating effects of the inhibitor, demonstrating that the changes in gene expression resulted from histidine-pathway blockage. These results show that plants are capable of cross-pathway metabolic regulation.

引用

页码：4997 / 5000

页数：4

共 37 条

[1] BREARS T, 1991, GENETIC ENG, V13, P221
[2] INCREASED ACTIVITY OF TRYPTOPHAN BIOSYNTHETIC ENZYMES IN HISTIDINE MUTANTS OF NEUROSPORA CRASSA
CARSIOTIS, M
LACY, AM
[J]. JOURNAL OF BACTERIOLOGY, 1965, 89 (06) : 1472 - +
[3] CROSS-PATHWAY REGULATION - HISTIDINE-MEDIATED CONTROL OF HISTIDINE, TRYPTOPHAN, AND ARGININE BIOSYNTHETIC ENZYMES IN NEUROSPORA-CRASSA
CARSIOTIS, M
JONES, RF
WESSELING, AC
[J]. JOURNAL OF BACTERIOLOGY, 1974, 119 (03) : 893 - 898
[4] PROLINE BIOSYNTHESIS AND OSMOREGULATION IN PLANTS
DELAUNEY, AJ
VERMA, DPS
[J]. PLANT JOURNAL, 1993, 4 (02) : 215 - 223
[5] CPC-1, THE GENERAL REGULATORY GENE FOR GENES OF AMINO-ACID BIOSYNTHESIS IN NEUROSPORA-CRASSA, IS DIFFERENTIALLY EXPRESSED DURING THE ASEXUAL LIFE-CYCLE
EBBOLE, DJ
PALUH, JL
PLAMANN, M
SACHS, MS
YANOFSKY, C
[J]. MOLECULAR AND CELLULAR BIOLOGY, 1991, 11 (02) : 928 - 934
[6] CLONING AND EXPRESSION IN YEAST OF A HIGHER-PLANT CHORISMATE MUTASE - MOLECULAR-CLONING, SEQUENCING OF THE CDNA AND CHARACTERIZATION OF THE ARABIDOPSIS-THALIANA ENZYME EXPRESSED IN YEAST
EBERHARD, J
RAESECKE, HR
SCHMID, J
AMRHEIN, N
[J]. FEBS LETTERS, 1993, 334 (02): : 233 - 236
[7] DIRECT GENETIC SELECTION OF A MAIZE CDNA FOR DIHYDRODIPICOLINATE SYNTHASE IN AN ESCHERICHIA-COLI DAPA- AUXOTROPH
FRISCH, DA
TOMMEY, AM
GENGENBACH, BG
SOMERS, DA
[J]. MOLECULAR & GENERAL GENETICS, 1991, 228 (1-2): : 287 - 293
[8] GOTTESMAN S, 1984, ANNU REV GENET, V18, P415
[9] HAWKES TR, 1993, IMIDAZOLE GLYCEROL P, V2, P739
[10] PRIMARY SITE OF ACTION OF AMITROLE IN ARABIDOPSIS-THALIANA INVOLVES INHIBITION OF ROOT ELONGATION BUT NOT OF HISTIDINE OR PIGMENT BIOSYNTHESIS
HEIM, DR
LARRINUA, IM
[J]. PLANT PHYSIOLOGY, 1989, 91 (03) : 1226 - 1231

← 1 2 3 4 →