ELECTRICAL CHANGES IN BRAIN IN COURSE OF EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS IN RABBITS

被引：4

作者：

FELDMAN, S

TAL, C

BEHAR, AJ

机构：

[1] Department of Nervous Diseases, Hadassah University Hospital, Hebrew University-Hadassah Medical School, Jerusalem

[2] Department of Pathology, Hadassah University Hospital, Hebrew University-Hadassah Medical School, Jerusalem

来源：

JOURNAL OF THE NEUROLOGICAL SCIENCES | 1969年 / 8卷 / 03期

关键词：

D O I：

10.1016/0022-510X(69)90002-1

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Electrical changes in the brain were studied daily in rabbits with permanently-implanted electrodes in the cortex and subcortical regions and were related to motor disturbances and to the observed skin reaction, following the induction of experimental allergic encephalomyelitis (EAE). All animals developed electrical abnormalities which were followed by motor weakness, but no correlation was found between the severity of these two phenomena. There was a clear relationship between the appearance of maximum skin reactivity and the onset of motor disturbances and to a lesser degree to the severity of the electrical changes in the brain, indicating that each of these phenomena are related to the same immunological mechanism. Early lesions showed perivascular infiltration while more chronic lesions showed glial proliferation and central necrosis. © 1969.

引用

页码：413 / &

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