GLUTATHIONE CONJUGATE OF PROSTAGLANDIN-A1 IS A BETTER SUBSTRATE THAN PROSTAGLANDIN-E FOR PARTIALLY PURIFIED AVIAN PROSTAGLANDIN-E 9-KETOREDUCTASE

被引：34

作者：

CAGEN, LM ^{[1
]}

PISANO, JJ ^{[1
]}

机构：

[1] NHLBI,CHEM LAB,PHYSIOL CHEM SECT,BETHESDA,MD 20014

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1979年 / 573卷 / 03期

关键词：

9-Ketoreductase; Glutathione-prostaglandin; Prostaglandin reduction;

D O I：

10.1016/0005-2760(79)90228-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The reduction of the glutathione conjugate of prostaglandin A1 by avian prostaglandin E 9-ketoreductase occurs at a faster rate than reduction of its presumed natural substrates, prostaglandin E1 or E2. © 1979.

引用

页码：547 / 551

页数：5

共 6 条

[1]

CAGEN LM, 1976, J BIOL CHEM, V251, P6550

[2]

CAGEN LM, 1977, FED P, V36, P714

[3]

LEE SC, 1975, J BIOL CHEM, V250, P4549

[4] DECREASED LEVELS OF AN INHIBITOR OF PROSTAGLANDIN-E 9-KETOREDUCTASE ACTIVITY IN CHICK DYSTROPHIC BREAST MUSCLE [J].

LEVINE, L ;

WU, KY .

NATURE, 1976, 260 (5554) :791-793

[5]

LOWRY OH, 1951, J BIOL CHEM, V193, P265

[6] NADP-LINKED 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE FROM HUMAN PLACENTA - PARTIAL-PURIFICATION AND CHARACTERIZATION OF ENZYME AND IDENTIFICATION OF AN INHIBITOR IN PLACENTAL TISSUE [J].

WESTBROOK, C ;

LIN, YM ;

JARABAK, J .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1977, 76 (03) :943-949

← 1 →