X-RAY ANALYSIS OF A PROGESTERONE-BINDING PROTEIN(UTEROGLOBIN) - PRELIMINARY-RESULTS

被引：16

作者：

MORNON, JP ^{[1
]}

SURCOUF, E ^{[1
]}

BALLY, R ^{[1
]}

FRIDLANSKY, F ^{[1
]}

MILGROM, E ^{[1
]}

机构：

[1] FAC MED PARIS SUD, INSERM, U135, GROUPE RECH BIOCHIM ENDOCRINIENNE & REPROD, F-94270 BICETRE, FRANCE

来源：

JOURNAL OF MOLECULAR BIOLOGY | 1978年 / 122卷 / 02期

关键词：

D O I：

10.1016/0022-2836(78)90038-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Uteroglobin, which is a progesterone-binding protein of the rabbit uterine secretion, has been crystallized and subjected to X-ray diffraction analysis. Two crystalline forms have been observed: a triclinic one (P1, Z = 2, a = 36.36 (4) A ̊, b = 37.40 (4) A ̊, c = 53.28 (4) A ̊, α = 104.6 (1) °, β = 97.0 (1) °, γ = 111.3(1) °); and an orthorhombic one for which the cell is C-centred with a = 50.86 (5)A ̊, b = 52.22 (5)A ̊, c = 47.28 (5) A ̊, space group C2221, Z = 4. Three isomorphous derivatives have been obtained. The crystals appear suitable for detailed study of the three-dimensional structure of the protein. © 1978.

引用

页码：237 / 239

页数：3

共 11 条

[1]

ATGER M, 1977, J BIOL CHEM, V252, P5412

[2] BINDING OF PROGESTERONE TO PROTEINS OF UTERINE LUMINAL FLUID - IDENTIFICATION OF UTEROGLOBIN AS BINDING-PROTEIN [J].