INSULIN-LIKE GROWTH FACTOR-I (IGF-1) IN BURN PATIENTS

被引：32

作者：

MOLLER, S

JENSEN, M

SVENSSON, P

SKAKKEBAEK, NE

机构：

[1] University Department of Growth and Reproduction, Rigshospitalet, Copenhagen

[2] University Department of Plastic Surgery, Burns Unit, Hvidovre Hospital, Copenhagen

来源：

BURNS | 1991年 / 17卷 / 04期

关键词：

D O I：

10.1016/0305-4179(91)90039-J

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Variations in growth factor IGF-1 levels during wound healing were assessed in 23 patients with burns of varying extent and severity. The patients were followed during the postburn period and the IGF-1 levels were regularly measured by radioimmunoassay. All patients with large burns had reduced IGF-1 levels which correlated with the surface area of burn. The most plausible reason for the suppressed IGF-1 level in these patients may be diffusion from the burned skin as we have found a strong correlation between IGF-1 and serum albumin. The reduced IGF-1 levels may contribute to impaired wound healing in these patients.

引用

页码：279 / 281

页数：3

共 26 条

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