CIS-ACTING CONTROL ELEMENTS 5' TO ALDA, THE ALDEHYDE DEHYDROGENASE-ENCODING GENE OF ASPERGILLUS-NIGER

被引：1

作者：

OCONNELL, MJ ^{[1
]}

KELLY, JM ^{[1
]}

机构：

[1] UNIV ADELAIDE,DEPT GENET,GPO BOX 498,ADELAIDE,SA 5001,AUSTRALIA

来源：

GENE | 1992年 / 117卷 / 01期

关键词：

GENE REGULATION; INDUCTION; CARBON CATABOLITE REPRESSION; ASPERGILLUS-NIDULANS;

D O I：

10.1016/0378-1119(92)90505-J

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The aldA gene of Aspergillus niger encodes an aldehyde dehydrogenase. Chromosomal deletion of this gene using gene replacement techniques has defined several growth conditions, thought to involve aldehyde and semialdehyde intermediates, that require this enzyme. Reintroduction of aldA clones carrying in vitro-generated deletions in the promoter region into the aldA deletion strain has been used to identify three elements controlling aldA expression: an enhancer required for high-level expression, an ethanol induction-responsive element, and a fructose induction-responsive element.

引用

页码：151 / 156

页数：6

共 16 条

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