PREPARATION OF CARBOCYCLIC PHOSPHONATE NUCLEOSIDES

被引：28

作者：

JAHNE, G

MULLER, A

KROHA, H

ROSNER, M

HOLZHAUSER, O

MEICHSNER, C

HELSBERG, M

WINKLER, I

RIESS, G

机构：

[1] HOECHST AG, SBU Antiinfectives - Research, 6230 Frankfurt am Main 80, G 838

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 37期

关键词：

D O I：

10.1016/S0040-4039(00)79086-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A versatile and high-yielding synthesis of racemic carbocyclic phosphonate nucleosides of adenine, hypoxanthine, guanine, cytosine, uracil, and thymine has been developed. These newly prepared compounds are isosteric (and isoelectronic) with (carbo)cyclic 2,3-dideoxy- and 2,3-dideoxy-2',3'-didehydronucleoside monophosphates.

引用

页码：5335 / 5338

页数：4

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