CYTOGENETIC ANALYSIS OF AN ADENOID CYSTIC CARCINOMA OF THE BARTHOLIN GLAND - A RARE, SEMIMALIGNANT TUMOR OF THE FEMALE GENITOURINARY TRACT

被引：12

作者：

KIECHLESCHWARZ, M ^{[1
]}

KOMMOSS, F ^{[1
]}

SCHMIDT, J ^{[1
]}

LUKOVIC, L ^{[1
]}

WALZ, L ^{[1
]}

BAUKNECHT, T ^{[1
]}

PFLEIDERER, A ^{[1
]}

机构：

[1] UNIV FREIBURG,DEPT GYNECOL & OBSTET,W-7800 FREIBURG,GERMANY

来源：

CANCER GENETICS AND CYTOGENETICS | 1992年 / 61卷 / 01期

关键词：

D O I：

10.1016/0165-4608(92)90365-F

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Cytogenetic analysis has been performed on short-term cultures from a 56-year-old woman suffering from an adenoid cystic carcinoma of Bartholin's gland. Beside a normal female karyotype, the tumor revealed an abnormal cell line with complex chromosome changes involving the chromosomes 1, 4, 6, 11, 22, and 14. The mainly structural and nonbalanced rearrangements led to the loss of the chromosome segments 1p31-->qter, 4q22-->q28, 6p12-->qter, 11p11.2-->pter, 14q24-->qter, and 22q13-->qter. Clonal numerical aberrations were not observed. To our knowledge, such a tumor has to-date not been cytogenetically investigated.

引用

页码：26 / 30

页数：5

共 20 条

[1] CHROMOSOME-1 ABERRATIONS IN CANCER [J].

ATKIN, NB .

CANCER GENETICS AND CYTOGENETICS, 1986, 21 (04) :279-285

[2]

BERSTEIN SG, 1983, AM J OBSTET GYNECOL, V147, P385

[3]

CHAMLIAN DL, 1972, OBSTET GYNECOL, V39, P489

[4]

COPELAND LJ, 1986, OBSTET GYNECOL, V67, P115

[5]

FOOTE FW, 1953, CANCER, V6, P1065, DOI 10.1002/1097-0142(195311)6:6<1065::AID-CNCR2820060602>3.0.CO

[6]

2-0

[7] RECESSIVE MECHANISMS OF MALIGNANCY [J].

GREEN, AR .

BRITISH JOURNAL OF CANCER, 1988, 58 (02) :115-121

[8]

HARNDEN DG, 1985, BIRTH DEFECTS ORIG 1, V21

[9]

HARNDEN DG, 1985, IN PRESS CYTOGENET C

[10] FINE STRUCTURE AND GENESIS OF CYLINDROMA (ADENOIDCYSTIC CARCINOMA) OF SALIVARY GLANDS - FURTHER INVESTIGATIONS ON ROLE OF MYOEPITHELIAL DIFFERENTIATED CELLS IN SALIVARY GLAND TUMORS [J].

HUBNER, G ;

KLEINSASSER, O ;

KLEIN, HJ .

VIRCHOWS ARCHIV ABTEILUNG A PATHOLOGISCHE ANATOMIE, 1969, 347 (04) :296-+

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