SOMATOSTATIN RECEPTOR ACTIVATION OF CELLULAR EFFECTOR SYSTEMS

被引：48

作者：

LAW, SF ^{[1
]}

WOULFE, D ^{[1
]}

REISINE, T ^{[1
]}

机构：

[1] UNIV PENN,SCH MED,DEPT PHARMACOL,PHILADELPHIA,PA 19104

来源：

CELLULAR SIGNALLING | 1995年 / 7卷 / 01期

关键词：

NEUROPEPTIDE; SOMATOSTATIN; G PROTEINS; RECEPTORS;

D O I：

10.1016/0898-6568(94)00064-I

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Somatostatin (SRIF) induces its multiple biological actions by interacting with a family of receptors, referred to as SSTR1-SSTR5. These receptors are capable of associating with particular guanine nucleotide binding proteins to couple the receptors to distinct cellular effector systems. Therefore, G proteins have an important role in directing SRIF signalling and may provide the molecular basis for the diverse cellular actions of SRIF.

引用

页码：1 / 8

页数：8