ANTITUMOR AGENTS .100. INHIBITION OF HUMAN DNA TOPOISOMERASE-II BY CYTO-TOXIC ETHER AND ESTER DERIVATIVES OF PODOPHYLLOTOXIN AND ALPHA-PELTATIN

被引：56

作者：

THURSTON, LS

IMAKURA, Y

HARUNA, M

LI, DH

LIU, ZC

LIU, SY

CHENG, YC

LEE, KH

机构：

[1] UNIV N CAROLINA,SCH PHARM,DIV MED CHEM & NAT PROD,NAT PROD LAB,CHAPEL HILL,NC 27599

[2] UNIV N CAROLINA,SCH MED,DEPT PHARMACOL,CHAPEL HILL,NC 27599

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1989年 / 32卷 / 03期

关键词：

D O I：

10.1021/jm00123a016

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：604 / 608

页数：5

共 15 条

[1]

BERNADY K, 1979, J ORG CHEM, V19, P1438

[2]

CHEN GL, 1984, J BIOL CHEM, V259, P3560

[3] PROTECTION OF HYDROXYL GROUPS AS TERT-BUTYLDIMETHYLSILYL DERIVATIVES [J].

COREY, EJ ;

VENKATESWARLU, A .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1972, 94 (17) :6190-+

[4]

GOTO T, 1984, J BIOL CHEM, V259, P422

[5]

HALLIGAN BD, 1985, J BIOL CHEM, V260, P2475

[6]

HARTWELL J, 1950, J AM CHEM SOC, V72, P247

[7]

HASSNER A, 1978, TETRAHEDRON LETT, V46, P4475

[8]

HSIEH T, 1983, J BIOL CHEM, V258, P8413

[9] MITOSIS INHIBITING NATURAL PRODUCTS .24. SYNTHESIS AND ANTIMITOTIC ACTIVITY OF GLYCOSIDIC LIGNAN DERIVATIVES RELATED TO PODOPHYLLOTOXIN [J].

KELLERJU.C ;

KUHN, M ;

WARTBURG, AV ;

STAHELIN, H .

JOURNAL OF MEDICINAL CHEMISTRY, 1971, 14 (10) :936-&

[10] MITOSIS INHIBITING NATURAL SUBSTANCES .22. PARTIAL SYNTHESIS OF 4'-DEMETHYLEPIPODOPHYLLOTOXIN [J].

KUHN, M ;

KELLERJU.C ;

VONWARTB.A .

HELVETICA CHIMICA ACTA, 1969, 52 (04) :944-&

← 1 2 →