CLASS-3 PORIN PROTEIN OF NEISSERIA-MENINGITIDIS - CLONING AND STRUCTURE OF THE GENE

被引:23
作者
BUTCHER, S [1 ]
SARVAS, M [1 ]
RUNEBERGNYMAN, K [1 ]
机构
[1] NATL PUBL HLTH INST,MOLEC BIOL PROGRAM,MANNERHEIMINTIE 166,SF-00300 HELSINKI 30,FINLAND
关键词
RECOMBINANT DNA; PORIN ALIGNMENT AND COMPARISON; N-GONORRHEA HOMOLOGY;
D O I
10.1016/0378-1119(91)90523-E
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
The gene coding for the class-3 protein of Neisseria meningitidis was cloned and sequenced. The deduced amino acid (aa) sequence was highly homologous (50-78%) to those of other neisserial porin proteins. Alignment of the aa sequence of five neisserial porin proteins pinpointed several regions of identity or near identity. These are assumed to be membrane-spanning beta-strands. A comparison of the homologies between these neisserial porins showed that the class-3 protein is most closely related to the Neisseria gonorrhoeae PIA protein.
引用
收藏
页码:125 / 128
页数:4
相关论文
共 22 条