CLASS-3 PORIN PROTEIN OF NEISSERIA-MENINGITIDIS - CLONING AND STRUCTURE OF THE GENE

被引：23

作者：

BUTCHER, S ^{[1
]}

SARVAS, M ^{[1
]}

RUNEBERGNYMAN, K ^{[1
]}

机构：

[1] NATL PUBL HLTH INST,MOLEC BIOL PROGRAM,MANNERHEIMINTIE 166,SF-00300 HELSINKI 30,FINLAND

来源：

GENE | 1991年 / 105卷 / 01期

关键词：

RECOMBINANT DNA; PORIN ALIGNMENT AND COMPARISON; N-GONORRHEA HOMOLOGY;

D O I：

10.1016/0378-1119(91)90523-E

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The gene coding for the class-3 protein of Neisseria meningitidis was cloned and sequenced. The deduced amino acid (aa) sequence was highly homologous (50-78%) to those of other neisserial porin proteins. Alignment of the aa sequence of five neisserial porin proteins pinpointed several regions of identity or near identity. These are assumed to be membrane-spanning beta-strands. A comparison of the homologies between these neisserial porins showed that the class-3 protein is most closely related to the Neisseria gonorrhoeae PIA protein.

引用

页码：125 / 128

页数：4

共 22 条

[1] THE CLASS-1 OUTER-MEMBRANE PROTEIN OF NEISSERIA-MENINGITIDIS - GENE SEQUENCE AND STRUCTURAL AND IMMUNOLOGICAL SIMILARITIES TO GONOCOCCAL PORINS
BARLOW, AK
HECKELS, JE
CLARKE, IN
[J]. MOLECULAR MICROBIOLOGY, 1989, 3 (02) : 131 - 139
[2] BLAKE MS, 1987, BACTERIAL OUTER MEMB, P377
[3] MOLECULAR-CLONING AND CHARACTERIZATION OF THE STRUCTURAL GENE FOR PROTEIN-I, THE MAJOR OUTER-MEMBRANE PROTEIN OF NEISSERIA-GONORRHOEAE
CARBONETTI, NH
SPARLING, PF
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (24) : 9084 - 9088
[4] GENETICS OF PROTEIN-I OF NEISSERIA-GONORRHOEAE - CONSTRUCTION OF HYBRID PORINS
CARBONETTI, NH
SIMNAD, VI
SEIFERT, HS
SO, M
SPARLING, PF
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (18) : 6841 - 6845
[5] PORIN PROTEIN OF NEISSERIA-GONORRHOEAE - CLONING AND GENE STRUCTURE
GOTSCHLICH, EC
SEIFF, ME
BLAKE, MS
KOOMEY, M
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (22) : 8135 - 8139
[6] HOLTEN E, 1979, J CLIN MICROBIOL, V9, P186
[7] PRIMARY STRUCTURE OF THE OMPF GENE THAT CODES FOR A MAJOR OUTER-MEMBRANE PROTEIN OF ESCHERICHIA-COLI K-12
INOKUCHI, K
MUTOH, N
MATSUYAMA, S
MIZUSHIMA, S
[J]. NUCLEIC ACIDS RESEARCH, 1982, 10 (21) : 6957 - 6968
[8] MOLECULAR DESIGN OF PHOE PORIN AND ITS FUNCTIONAL CONSEQUENCES
JAP, BK
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1989, 205 (02) : 407 - 419
[9] KLEBBA PE, 1990, J BIOL CHEM, V265, P6800
[10] DEDUCED AMINO-ACID-SEQUENCES OF CLASS-1 PROTEIN (PORA) FROM 3 STRAINS OF NEISSERIA-MENINGITIDIS - SYNTHETIC PEPTIDES DEFINE THE EPITOPES RESPONSIBLE FOR SEROSUBTYPE SPECIFICITY
MCGUINNESS, B
BARLOW, AK
CLARKE, IN
FARLEY, JE
ANILIONIS, A
POOLMAN, JT
HECKELS, JE
[J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1990, 171 (06) : 1871 - 1882

← 1 2 3 →