NALOXONE REVERSAL OF HYPOTENSION DUE TO CAPTOPRIL OVERDOSE

被引：20

作者：

VARON, J ^{[1
]}

DUNCAN, SR ^{[1
]}

机构：

[1] STANFORD UNIV,MED CTR,DEPT MED,STANFORD,CA 94305

来源：

ANNALS OF EMERGENCY MEDICINE | 1991年 / 20卷 / 10期

关键词：

captopril; overdose; naloxone; captopril overdose;

D O I：

10.1016/S0196-0644(05)81389-7

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

The hemodynamic effects of captopril and other angiotensin-converting enzyme inhibitors may be mediated by the endogenous opioid system. The opioid antagonist naloxone has been shown to block or reverse the hypotensive actions of captopril. We report a case of an intentional captopril overdose, manifested by marked hypotension, that resolved promptly with the administration of naloxone. To our knowledge, this is the first reported case of captopril-induced hypotension treated with naloxone. Our experience demonstrates a possible role of naloxone in the reversal of hypotension resulting from captopril.

引用

页码：1125 / 1127

页数：3

共 18 条

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