EFFECTS OF FIBROBLAST GROWTH-FACTOR AND BROMOCRIPTINE ON THE MITOTIC-ACTIVITY OF THE ANTERIOR-PITUITARY GLAND IN ORGAN-CULTURE

被引:8
作者
PAWLIKOWSKI, M
STEPIEN, H
机构
[1] Department of Experimental Endocrinology, Institute of Endocrinology, School of Medicine, Łódź
关键词
Anterior pituitary; Bromocriptine; Fibroblast growth factor; Mitotic activity;
D O I
10.1007/BF00239229
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Effects of fibroblast growth factor (FGF) and of bromocriptine, a dopaminergic receptor agonist, on the mitotic index in the organ-cultured anterior pituitary gland of the rat were investigated, using the colchicine metaphase-arrest technique. It has been found that FGF increases the mitotic index in the anterior pituitary explants. By contrast bromocriptine inhibits the mitogenic effect of FGF. © 1979 Springer-Verlag.
引用
收藏
页码:165 / 169
页数:5
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