THERAPEUTIC AND TOXIC LEVELS OF PHENIRAMINE IN BIOLOGICAL SPECIMENS

被引:8
作者
QUEREE, EA [1 ]
DICKSON, SJ [1 ]
MISSEN, AW [1 ]
PANNELL, LK [1 ]
机构
[1] DEPT SCI & IND RES,DIV CHEM,CHRISTCHURCH,NEW ZEALAND
关键词
D O I
10.1093/jat/3.6.253
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
A method involving gas-fiquid chromatography with nitrogenphosphorus detection is presented for the determination of toxic and therapeutic pheniramine levels in blood and toxic levels in tissue. Therapeutic levels of pheniramine in six subjects two hours after taking 75 mg pheniramine maleate were found to vary from 0.01 to 0.190μg/mL of blood. Blood and tissue levels from two postmortem cases are reported. © 1979 Oxford University Press.
引用
收藏
页码:253 / 255
页数:3
相关论文
共 8 条