ENANTIOSELECTIVE SYNTHESIS OF (-)-GEPHYROTOXINE-223AB [(3R,5R,9R)-3-BUTYL-5-PROPYLOCTAHYDROINDOLIZINE]

被引：31

作者：

FLEURANT, A ^{[1
]}

CELERIER, JP ^{[1
]}

LHOMMET, G ^{[1
]}

机构：

[1] UNIV PARIS 06,CHIM HETEROCYCLES LAB,CNRS,ERS 73,4 PL JUSSIEU,F-75252 PARIS 05,FRANCE

来源：

TETRAHEDRON-ASYMMETRY | 1993年 / 4卷 / 07期

关键词：

D O I：

10.1016/S0957-4166(00)80332-8

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A highly enantioselective synthesis of the dendrobatid indolizidine alkaloid 223AB is described using a chiral amino acid as starting material.

引用

收藏

页码：1429 / 1430

页数：2

相关论文

共 9 条

[1] COREY EJ, 1975, TETRAHEDRON LETT, P2647
[2] Daly J. W., 1986, ALKALOIDS CHEM BIOL, V4, P1
[3] ENANTIOSELECTIVE SYNTHESIS OF (5R,9R)-5-PROPYL-OCTAHYDROINDOLIZINE [(-)-GEPHYROTOXIN 167B]
FLEURANT, A
CELERIER, JP
LHOMMET, G
[J]. TETRAHEDRON-ASYMMETRY, 1992, 3 (06) : 695 - 696
[4] FLEURANT A, IN PRESS HETEROCYCLE
[5] GENERAL ENTRY TO THE 3,5-DISUBSTITUTED INDOLIZIDINE CLASS OF DENDROBATID ALKALOIDS - TOTAL SYNTHESES OF BOTH ENANTIOMERS OF INDOLIZIDINES 195B, 223AB, 239AB, AND 239CD FROM A COMMON CHIRAL SYNTHON
MACHINAGA, N
KIBAYASHI, C
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1992, 57 (19) : 5178 - 5189
[6] ASYMMETRIC-SYNTHESIS .3. ENANTIOSPECIFIC SYNTHESIS OF THE NATURAL 3R, 5R, 9R (-) GEPHYROTOXIN-223 AB
ROYER, J
HUSSON, HP
[J]. TETRAHEDRON LETTERS, 1985, 26 (12) : 1515 - 1518
[7] TOTAL SYNTHESIS OF (+) MONOMORINE-I FROM CHIRAL CYCLIC BETA-ENAMINO ESTER
SALIOU, C
FLEURANT, A
CELERIER, JP
LHOMMET, G
[J]. TETRAHEDRON LETTERS, 1991, 32 (28) : 3365 - 3368
[8] THE STRUCTURE OF GEPHYROTOXIN (GTX) 223AB
SPANDE, TF
DALY, JW
HART, DJ
TSAI, YM
MACDONALD, TL
[J]. EXPERIENTIA, 1981, 37 (12): : 1242 - 1245
[9] ENANTIOSELECTIVE RU-MEDIATED SYNTHESIS OF (-)-INDOLIZIDINE-223AB
TABER, DF
DEKER, PB
SILVERBERG, LJ
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1992, 57 (22) : 5990 - 5994