PALLADIUM-CATALYZED INTRAMOLECULAR CYANOSILYLATION OF ALKYNES LEADING TO STEREOSELECTIVE SYNTHESIS OF ALPHA,BETA-UNSATURATED NITRILES

被引：70

作者：

SUGINOME, M ^{[1
]}

KINUGASA, H ^{[1
]}

ITO, Y ^{[1
]}

机构：

[1] KYOTO UNIV,FAC ENGN,DEPT SYNTHET CHEM & BIOL CHEM,KYOTO 60601,JAPAN

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 46期

关键词：

D O I：

10.1016/S0040-4039(00)78457-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Intramolecular cyanosilylation was achieved by the reaction of chlorodiphenylsilyl ether of homopropargylic alcohols with trimethylsilylcyanide in the presence of palladium catalyst The reaction proceeded regio- and stereoselectively to give (Z)-3-(1-cyanoalkylidene)-2-silatetrahydrofurans, whose silyl group was transformed into various organic groups.

引用

页码：8635 / 8638

页数：4

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