ACETOHYDROXAMIC ACIDS AS POTENT, SELECTIVE, ORALLY ACTIVE 5-LIPOXYGENASE INHIBITORS

被引：59

作者：

JACKSON, WP ^{[1
]}

ISLIP, PJ ^{[1
]}

KNEEN, G ^{[1
]}

PUGH, A ^{[1
]}

WATES, PJ ^{[1
]}

机构：

[1] SCHERING AGROCHEM LTD,CHESTERFORD PK RES STN,ESSEX CB10 1XL,ENGLAND

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1988年 / 31卷 / 03期

关键词：

D O I：

10.1021/jm00398a001

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

收藏

页码：499 / 500

页数：2

相关论文

共 20 条

[1] BISGAARD H, 1982, PROSTAGLANDINS, V23, P801
[2] LEUKOTRIENES IN INFLAMMATION
BRAY, MA
[J]. AGENTS AND ACTIONS, 1986, 19 (1-2): : 87 - 99
[3] THE PHARMACOLOGY AND PATHO-PHYSIOLOGY OF LEUKOTRIENE-B4
BRAY, MA
[J]. BRITISH MEDICAL BULLETIN, 1983, 39 (03) : 249 - 254
[4] LEUKOTRIENE BIOSYNTHESIS INHIBITORS
CASHMAN, JR
[J]. PHARMACEUTICAL RESEARCH, 1985, (06) : 253 - 261
[5] RATIONALLY DESIGNED, POTENT COMPETITIVE INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS
COREY, EJ
CASHMAN, JR
KANTNER, SS
WRIGHT, SW
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1984, 106 (05) : 1503 - 1504
[6] GARDINER PJ, 1987, DRUGS AFFECTING LEUK
[7] NEW APPROACH TO ANTI-INFLAMMATORY DRUGS
HIGGS, GA
FLOWER, RJ
VANE, JR
[J]. BIOCHEMICAL PHARMACOLOGY, 1979, 28 (12) : 1959 - 1961
[8] HIGGS GA, IN PRESS BR J PHARM
[9] KERDESKY FAJ, 1985, TETRAHEDRON LETT, P2143
[10] STEREOCONTROLLED TOTAL SYNTHESIS OF (5Z,8Z,11Z,13E)(15S)-15-HYDROXYEICOSA-5,8,11,13-TETRAENOIC ACID (15S-HETE) AND ANALOGS
NICOLAOU, KC
LADDUWAHETTY, T
ELISSEOU, EM
[J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1985, (22) : 1580 - 1581