LIGHT AND ELECTRON-MICROSCOPIC STUDY OF AN OVARIAN AND RECTAL CARCINOID

被引：14

作者：

WILLIAMS, RM

机构：

[1] Gibson Laboratories, University of Oxford, Radcliffe Infirmary, Oxford

来源：

HISTOPATHOLOGY | 1979年 / 3卷 / 01期

关键词：

APUD; argentaffin; argyrophil; carcinoid; electron microscopy; ovary; rectum;

D O I：

10.1111/j.1365-2559.1979.tb02978.x

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

An ovarian and rectal carcinoid within the same person is described. The ovarian carcinoid is non‐argentaffinic with typical regular granules. The rectal tumour consists of two types of APUD cells, some argentaffinic and diazo‐positive, whilst others are non‐argyrophilic. These features are mirrored ultrastructurally, some cells containing the large pleomorphic argentaffinic granules while others have smaller regular granules. In addition, focal aggregates of microfilaments were found in both tumour types. These findings are discussed in terms of the APUD concept. The similarities of the APUD tumour cells to D1 APUD cells of the duodenum is highlighted, and an alternative explanation for their derivation is proposed. Copyright © 1979, Wiley Blackwell. All rights reserved

引用

页码：19 / 30

页数：12

共 17 条

[1]

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