POLYAMINES AND GLUTATHIONE IN TISSUES OF LACTATING RATS (RATTUS RATTUS) AND IN RD/3 ASCITES TUMOUR

被引：23

作者：

NEISH, WJP

KEY, L

机构：

[1] Department of Pharmacology, The University, Sheff

来源：

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY | 1968年 / 27卷 / 03期

关键词：

D O I：

10.1016/0010-406X(68)90611-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1. 1. Polyamines and glutathione were determined in tissues of lactating and normal female rats and in an ascites form of rat Rd/3 sarcoma. 2. 2. During lactation, rat liver glutathione decreased and spermidine/spermine increased. Similar but more pronounced changes had previously been found in livers of pregnant rat or rats bearing solid Rd/3 sarcoma. 3. 3. Lactating mammary tissue has a very high spermidine content and sperdimine/spermine ratio, similar to values found in a mouse ascites tumour by other workers. However, the ascites form of Rd/3 sarcoma had the same lower polyamine and glutathione levels as the solid Rd/3 tumour. © 1968.

引用

页码：709 / &

共 7 条

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NEISH, WJP
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[5] SPERMIDINE SPERMINE AND GLUTATHIONE IN RD/3 SARCOMA RATS
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[6] TABOR H, 1964, PHARMACOL REV, V16, P245
[7] UGAMI S., 1955, JOUR JAPANESE BIOCHEM SOC, V27, P133

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