INVITRO EVALUATION OF INFLAMMATORY CELL RESPONSE AFTER CF4 PLASMA SURFACE MODIFICATION OF POLY(METHYL METHACRYLATE) INTRAOCULAR LENSES

被引：39

作者：

ELOY, R ^{[1
]}

PARRAT, D ^{[1
]}

DUC, TM ^{[1
]}

LEGEAY, G ^{[1
]}

BECHETOILLE, A ^{[1
]}

机构：

[1] UNIV LYON 1,CENATS IPN LYON,43 BLVD 11 NOVEMBRE 1918,F-69622 VILLEURBANNE,FRANCE

来源：

JOURNAL OF CATARACT AND REFRACTIVE SURGERY | 1993年 / 19卷 / 03期

关键词：

GRANULOCYTE ACTIVATION; INFLAMMATORY CELL RESPONSE; INTRAOCULAR LENS; PLASMA TREATMENT; POLY(METHYL METHACRYLATE); SURFACE MODIFICATION;

D O I：

10.1016/S0886-3350(13)80307-0

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

The inflammatory cell response of tetrafluorocarbon (CF4) plasma surface modification of poly(methyl methacrylate) intraocular lenses (IOLs) was investigated in vitro. After two hours of lens contact with human granulocytes, scanning electron microscopy showed significantly less cell activation and granulocyte adhesion on the surface-modified IOL than on the untreated IOL (P < .01). The x-ray photoelectron spectroscopy analysis of the CF4 plasma surface modification demonstrated that new compounds containing fluorine were homogeneously grafted onto the PMMA lens surface, resulting in a marked increase of contact angle. These in vitro results must be confirmed by in vivo studies of CF4 plasma surface modification of IOLs.

引用

页码：364 / 370

页数：7

共 19 条

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