CONGENITAL NEPHROGENIC DIABETES-INSIPIDUS IN AN ADULT

被引：3

作者：

ISHII, H

MIZUNO, K

NIIMURA, S

HAGA, H

TAKAHASHI, M

WATANABE, Y

TANAKA, K

OGATA, M

TANAKA, N

FUKUCHI, S

机构：

[1] Third Department of Internal Medicine, Fukushima Medical College, Fukushima

[2] Physical Health Care Center, Fukushima University, Fukushima

[3] Pathology and Cytology Laboratory, BML, Tokyo

来源：

INTERNAL MEDICINE | 1993年 / 32卷 / 02期

关键词：

MITOCHONDRIA; KIDNEY BIOPSY; BRUSH-BORDER; TRICHLORMETHIAZIDE; TRIAMTERENE;

D O I：

10.2169/internalmedicine.32.133

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

A 35-year-old man with congenital nephrogenic diabetes insipidus (NDI) is reported. Renal biopsy revealed miniaturized and rounded mitochondria of the proximal tubular cells and decreased brush-borders. Trichlormethiazide combined with triamterene resulted in an apparent reduction of daily urine volume and concomitant increment in urine osmolarity. The present case seems rare in that some morphological changes in the renal tissues could be demonstrated in an adult case with congenital NDI.

引用

页码：133 / 138

页数：6

共 9 条

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