COMBINED HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY AND RADIOIMMUNOASSAY METHOD FOR THE ANALYSIS OF DELTA-9-TETRAHYDROCANNABINOL METABOLITES IN HUMAN-URINE

被引：28

作者：

WILLIAMS, PL

MOFFAT, AC

KING, LJ

机构：

[1] HOME OFF CENT RES ESTAB,READING RG7 4PN,BERKSHIRE,ENGLAND

[2] UNIV SURREY,DEPT BIOCHEM,GUILDFORD GU2 5XH,SURREY,ENGLAND

来源：

JOURNAL OF CHROMATOGRAPHY | 1979年 / 186卷 / DEC期

关键词：

D O I：

10.1016/S0021-9673(00)95280-4

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A high-performance liquid chromatography-radioimmunoassay method for the measurement of cannabinoids in urine is described. The method involves chromatographing a hydroloysed urine sample with high-performance liquid chromatography and quantifying the eluting cross-reacting cannabinoids with radioimmunoassay. It has been applied to the analysis of cannabinoids in human urine obtained from subjects who had smoked Δ9-tetrahydrocannabinol and the identities of some of the cross-reacting cannabinoids have been established by gas chromatographymass spectrometry. The method is suitable for use as a routine procedure for cannabinoid analysis in urine. © 1979.

引用

页码：595 / 603

页数：9

共 14 条

[1] QUANTITATION OF DELTA1-TETRAHYDROCANNABINOL IN PLASMA FROM CANNABIS SMOKERS
AGURELL, S
GUSTAFSS.B
HOLMSTED.B
LEANDER, K
LINDGREN, JE
NILSSON, I
SANDBERG, F
ASBERG, M
[J]. JOURNAL OF PHARMACY AND PHARMACOLOGY, 1973, 25 (07) : 554 - 558
[2] ANDERSEN JM, 1971, ACTA PHARMACOL TOX, V29, P111
[3] CHASE AR, 1976, RES MONOGR SER NATL, V7, P1
[4] CANNABIS METABOLITES IN URINE AFTER ORAL ADMINISTRATION
CHRISTIANSEN, J
RAFAELSEN, OJ
[J]. PSYCHOPHARMACOLOGIA, 1969, 15 (01): : 60 - +
[5] GROSS SJ, 1976, RES MONOGR SER NATL, V7, P10
[6] KANTER SL, 1971, CLIN CHEM, V17, P636
[7] MEASUREMENT OF CANNABINOLS IN BLOOD BY GAS-CHROMATOGRAPHY
MCCALLUM, NK
[J]. JOURNAL OF CHROMATOGRAPHIC SCIENCE, 1973, 11 (10) : 509 - 511
[8] RECENT ADVANCES IN CHEMISTRY AND BIOCHEMISTRY OF CANNABIS
MECHOULAM, R
MCCALLUM, NK
BURSTEIN, S
[J]. CHEMICAL REVIEWS, 1976, 76 (01) : 75 - 112
[9] NORDQVIST M, 1976, RES MONOGR SER NAT I, V7, P64
[10] PROBLEMS CONCERNING RELIABLE IDENTIFICATION OF HASHISH IN URINE BY THIN-LAYER CHROMATOGRAPHY
SALASCHE.M
MATTE, A
SEIFERT, R
[J]. JOURNAL OF CHROMATOGRAPHY, 1973, 78 (02): : 393 - 400

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