FUNCTIONAL-SIGNIFICANCE OF WHITE BLOOD-CELLS IN THE MALE AND FEMALE REPRODUCTIVE-TRACT

被引：110

作者：

BARRATT, CLR

BOLTON, AE

COOKE, ID

机构：

[1] Harris Birthright Centre for Reproductive Medicine, University Department of Obstetrics and Gynaecology, Jessop Hospital for Women

[2] Department of Biomedical Sciences, Sheffield City Polytechnic

来源：

HUMAN REPRODUCTION | 1990年 / 5卷 / 06期

基金：

英国医学研究理事会;

关键词：

Anti-sperm antibodies; Cytokines; Leukocytes; Spermatozoa; Transport;

D O I：

10.1093/oxfordjournals.humrep.a137162

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The functional significance of white blood cells in the modulation of an anti-sperm antibody response, prevention of infection (including HIV) sperm transport/storage and sperm function is extensively discussed. A critical review of the existing literature is presented with future experimental lines of investigation outlined. A lack of controlled clinical studies in the human to validate data from animal species-for example-the involvement of white blood cells in the transport and storage of sperm in the female tract and the possible adverse effect of pathology (i.e. endometriosis) on these functions are presented. In conclusion, with the advent of modern techniques, e.g. monoclonal antibodies and sophisticated sperm function tests, many of the questions raised should be answered in the near future. © 1990 Oxford University Press.

引用

页码：639 / 648

页数：10

共 88 条

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