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DOES BULK DAMAGE TO DNA EXPLAIN THE CYTOSTATIC AND CYTOTOXIC EFFECTS OF TOPOISOMERASE-II INHIBITORS

被引：51
作者：
GEWIRTZ, DA
机构：
[1] Department of Pharmacology/Toxicology, Medical College of Virginia, Richmond
来源：
BIOCHEMICAL PHARMACOLOGY | 1991年 / 42卷 / 12期
关键词：
D O I：
10.1016/0006-2952(91)90227-V
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
[No abstract available]
引用
收藏
页码：2253 / 2258
页数：6
相关论文
共 78 条
[1]  
[Anonymous], [No title captured]
[2]  
ARMSTRONG RD, 1986, P AM ASSOC CANC RES, V27, P19
[3]   EFFECT OF 1-BETA-D-ARABINOFURANOSYLCYTOSINE (ARA-C) ON NUCLEAR TOPOISOMERASE-II ACTIVITY AND ON THE DNA CLEAVAGE AND CYTO-TOXICITY PRODUCED BY 4'-(9-ACRIDINYLAMINO)METHANESULFON-META-ANISIDIDE (META-AMSA) AND ETOPOSIDE IN META-AMSA-SENSITIVE AND META-AMSA-RESISTANT HUMAN-LEUKEMIA CELLSD [J].
BAKIC, M ;
CHAN, D ;
ANDERSSON, BS ;
BERAN, M ;
SILBERMAN, L ;
ESTEY, E ;
RICKETTS, L ;
ZWELLING, LA .
BIOCHEMICAL PHARMACOLOGY, 1987, 36 (23) :4067-4077
[4]   THE PRODUCTION OF TOPOISOMERASE-II-MEDIATED DNA CLEAVAGE IN HUMAN-LEUKEMIA CELLS PREDICTS THEIR SUSCEPTIBILITY TO 4'-(9-ACRIDINYLAMINO)METHANESULFON-M-ANISIDIDE (M-AMSA) [J].
BAKIC, M ;
BERAN, M ;
ANDERSSON, BS ;
SILBERMAN, L ;
ESTEY, E ;
ZWELLING, LA .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1986, 134 (02) :638-645
[5]  
BELLAMY WT, 1988, CANCER RES, V48, P6303
[6]   CELL-DEATH INDUCED BY TOPOISOMERASE INHIBITORS - ROLE OF CALCIUM IN MAMMALIAN-CELLS [J].
BERTRAND, R ;
KERRIGAN, D ;
SARANG, M ;
POMMIER, Y .
BIOCHEMICAL PHARMACOLOGY, 1991, 42 (01) :77-85
[7]   PROTECTION OF DOXORUBICIN CYTO-TOXICITY BY CYCLOHEXIMIDE [J].
BONNER, JA ;
LAWRENCE, TS .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1989, 16 (05) :1209-1212
[8]   LOCAL SEQUENCE REQUIREMENTS FOR DNA CLEAVAGE BY MAMMALIAN TOPOISOMERASE-II IN THE PRESENCE OF DOXORUBICIN [J].
CAPRANICO, G ;
KOHN, KW ;
POMMIER, Y .
NUCLEIC ACIDS RESEARCH, 1990, 18 (22) :6611-6619
[9]   SEQUENCE-SELECTIVE TOPOISOMERASE-II INHIBITION BY ANTHRACYCLINE DERIVATIVES IN SV40 DNA - RELATIONSHIP WITH DNA-BINDING AFFINITY AND CYTOTOXICITY [J].
CAPRANICO, G ;
ZUNINO, F ;
KOHN, KW ;
POMMIER, Y .
BIOCHEMISTRY, 1990, 29 (02) :562-569
[10]  
CAPRANICO G, 1989, CANCER RES, V49, P2022
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