ASSESSMENT OF THE CARIOGENIC POTENTIAL OF STREPTOCOCCUS-MUTANS STRAINS AND ITS RELATIONSHIP TO INVIVO CARIES EXPERIENCE

被引:11
作者
MACPHERSON, LMD
MACFARLANE, TW
GEDDES, DAM
STEPHEN, KW
机构
[1] Department of Oral Medicine and Pathology, University of Glasgow Dental School
[2] Department of Oral Biology, University of Glasgow Dental School
来源
ORAL MICROBIOLOGY AND IMMUNOLOGY | 1992年 / 7卷 / 03期
关键词
STREPTOCOCCUS-MUTANS; CARIOGENIC POTENTIAL; INVITRO MODEL; INTRAORAL CARIES;
D O I
10.1111/j.1399-302X.1992.tb00527.x
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Strains of Streptococcus mutans isolated from the plaque of 6 subjects were studied using an in vitro model to determine whether differences in their cariogenic potential could be detected, and if so, whether the results correlated with the caries experience of the individuals. Each strain was incubated with a bovine enamel slab and 5% (w/v) sucrose for 24-h periods. The acidogenic potential was assessed by PH measurement and analysis of acid anion production. Microradiographic and microdensitometric assessment of the enamel, together with measurement of the change in calcium concentration of the reaction mixture were used to determine the demineralizing potential of each strain. Significant differences in cariogenic potential were found between some of the strains tested, and correlations were found between 3 of the test parameters and the decayed-missing-filled-surface score of the individuals. The results suggest that the caries experience of individuals may be related, to some extent, to the cariogenic potential of their S. mutans strains.
引用
收藏
页码:142 / 147
页数:6
相关论文
共 31 条
[1]  
Alaluusua S, Renkonen O-V, Streptococcus mutans establishment and dental caries experience in children from 2 to 4 years old, Scand J Dent Res, 91, pp. 453-457, (1983)
[2]  
Crossner C-G, Salivary lactobacillus counts in the prediction of caries activity, Community Dent Oral Epidemiol, 9, pp. 182-190, (1981)
[3]  
Dirksen TR, Little MF, Bibby BG, The pH of carious cavities. II. The pH at different depths in isolated cavities, Arch Oral Biol, 8, pp. 91-97, (1963)
[4]  
Disller W, Kroncke A, The acid pattern in human dental plaque, J Dent Res, 62, pp. 87-91, (1983)
[5]  
Geddes DAM, Acids produced by human denial plaque metabolism in situ, Caries Res, 9, pp. 98-109, (1975)
[6]  
Geddes DAM, Studies on metabolism of dental plaque. Diffusion and acid production in human dental plaque, Frontiers of oral physiology, 3, pp. 78-87, (1981)
[7]  
Geddes DAM, Weetman DA, Featherstone JDB, Preferential loss of acetic acid from plaque fermentation in the presence of enamel, Caries Res, 18, pp. 430-433, (1984)
[8]  
Hamilton IR, Boyar RM, Bowden GH, Influence of pH and fluoride on properties of an oral strain of Lactobacillus casei grown in continuous culture, Infect Immun, 48, pp. 664-670, (1985)
[9]  
Hamilton IR, Ellwood DC, Effects of fluoride on carbohydrate metabolism by washed cells of Streptococcus mutans Ingbritt grown at various pH values in a chemostat, Infect Immun, 19, pp. 434-442, (1978)
[10]  
Hardie JM, Thomson PL, South RJ, Et al., A longitudinal epidemiological study on dental plaque and the development of dental caries ‐ interim results after two years, J Dent Res, 56, (1977)