THE REMOVAL OF HUMAN LEUKEMIA-CELLS FROM BLOOD USING INTERDIGITATED MICROELECTRODES

被引:159
作者
BECKER, FF [1 ]
WANG, XB [1 ]
HUANG, Y [1 ]
PETHIG, R [1 ]
VYKOUKAL, J [1 ]
GASCOYNE, PRC [1 ]
机构
[1] UNIV WALES, INST MOLEC & BIOMOLEC ELECTR, BANGOR LL57 1UT, WALES
关键词
D O I
10.1088/0022-3727/27/12/030
中图分类号
O59 [应用物理学];
学科分类号
摘要
An electroaffinity column containing an interdigitated microelectrode array was used to retain human leukaemia cells dielectrophoretically and thereby separate them from normal blood cells. The leukaemic cells could be subsequently released by removal of the dielectrophoretic field and collected. This novel approach exploits the differential dielectric properties of cells as a sorting criterion and has applications in medicine, biotechnology and environmental settings.
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页码:2659 / 2662
页数:4
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