ANALYSIS OF DUODENAL CONTRACTILITY IN THE UNANESTHETIZED DOG

被引:7
作者
ENGSTROM, ER
WEBSTER, JG
BASS, P
机构
[1] UNIV WISCONSIN,CTR INSTRUMENTAT SYST,MADISON,WI 53706
[2] UNIV WISCONSIN,DEPT ELECT & COMP ENGN,MADISON,WI 53706
[3] UNIV WISCONSIN,SCH MED,DEPT PHARMACOL,MADISON,WI 53706
[4] UNIV WISCONSIN,SCH PHARM,MADISON,WI 53706
关键词
D O I
10.1109/TBME.1979.326434
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
The temporal relationship of circular muscle contractions at eight positions spaced at 2.5 cm intervals along the duodenum was determined after administration of test meals and drugs in dogs chronically implanted with strain-gage force transducers. An automatic data analysis system was developed to 1) recognize contractions, 2) measure contractile amplitudes and intercontractile intervals, 3) perform statistical calculations, and 4) present results in various different formats. Under virtually all test conditions, when propagated contractions were present, the mean propagation was in a caudad direction. Two specific results indicate that after feeding, duodenal contractions produce a greater mixing action. The percentage of contractions which were propagated between adjacent transducer locations was significantly (p < 0.05) decreased from that of an interdigestive state when the animals received canned dog food. The minimum interval between contractions at a particular transducer position increased significantly (p < 0.05) from that of an interdigestive stage when a citrate plus fat test meal was administered. © 1979 SDAIEEE
引用
收藏
页码:517 / 523
页数:7
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