Biosynthesis of Corrins: the C-Methylation Steps

被引：26

作者：

Battersby, Alan R. ^{[1
]}

Ihara, Masataka ^{[1
]}

McDonald, Edward ^{[1
]}

Stephenson, Janet R. ^{[1
]}

Golding, Bernard T. ^{[2
]}

机构：

[1] Univ Chem Lab, Cambridge CB2 1EW, England

[2] Univ Warwick, Dept Mol Sci, Coventry CV4 7AL, W Midlands, England

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1974年 / 12期

关键词：

D O I：

10.1039/c39740000458

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Biological derivation of the Pro-R methyl group at C-12 of vitamin B(12) from methionine is confirmed by both (13)C and (2)H labelling and the methyl groups at C-7 and C-12 are shown to be incorporated intact.

引用

页码：458 / U4

页数：2

共 7 条

[1] BIOSYNTHESIS OF VITAMIN-B12 - MACROCYCLE AND STUDIES ON GEMINAL METHYL GROUPS OF RING-C
BATTERSBY, AR
IHARA, M
MCDONALD, E
STEPHENSON, JR
GOLDING, BT
[J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1973, (12) : 404 - 405
[2] CYANO-13-EPICOBALAMIN (NEOVITAMIN-B12) AND ITS RELATIVES
BONNETT, R
GODFREY, JM
MATH, VB
[J]. JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC, 1971, (22): : 3736 - &
[3] BRAY RC, 1963, J BIOL CHEM, V238, P1501
[4] PROTON MAGNETIC RESONANCE STUDIES OF VITAMIN-B12 - PROTON MAGNETIC RESONANCE SPECTRA OF SOME COBALAMINS AND COBINAMIDES
BRODIE, JD
POE, M
[J]. BIOCHEMISTRY, 1971, 10 (05) : 914 - &
[5] BROWN CE, 1973, J BIOL CHEM, V248, P8015
[6] DUBS P, THESIS
[7] STEREOCHEMISTRY OF METHYL GROUP INSERTION IN CORRINOID BIOSYNTHESIS - DETERMINATION OF CARBON ISOTOPE CHIRALITY BY C-13 NUCLEAR MAGNETIC-RESONANCE
SCOTT, AI
CUSHLEY, RJ
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1973, 95 (17) : 5759 - 5761

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