The use of Photodynamic Therapy (PDT) for the Treatment of Superficial Tumours on the Bladder Wall

被引:12
作者
Stamp, J. M. [1 ]
Fowler, G. J. S. [2 ]
Devonshire, R. [2 ]
Williams, J. L. [3 ]
机构
[1] Royal Hallamshire Hosp, Dept Med Phys & Clin Engn, Sheffield S10 2JF, S Yorkshire, England
[2] Univ Sheffield, Dept Chem, Sheffield S6 7HF, S Yorkshire, England
[3] Royal Hallamshire Hosp, Dept Urol, Sheffield S10 2JF, S Yorkshire, England
关键词
Photodynamic therapy; Superficial bladder tumours; Dosimetry; Isotropic light sensors; Photosensitizers; Wavelength of irradiation;
D O I
10.1007/BF02032616
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
The use of photodynamic therapy (PDT) for the treatment of superficial tumours on the bladder wall is described. Details are given on the laser, methods of delivering light into the bladder, suitable commercial dosimetry systems and instrumentation suitable for making light measurements on the bladder wall during therapy. New alternative photosensitizers are discussed in some detail. Some early clinical results are presented and the current problems with this type of therapy are highlighted.
引用
收藏
页码:5 / 12
页数:8
相关论文
共 26 条
[1]   BIOLOGICAL-ACTIVITIES OF PHTHALOCYANINES .10. SYNTHESES AND ANALYSES OF SULFONATED PHTHALOCYANINES [J].
ALI, H ;
LANGLOIS, R ;
WAGNER, JR ;
BRASSEUR, N ;
PAQUETTE, B ;
VANLIER, JE .
PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1988, 47 (05) :713-717
[2]   THE USE OF LIPID EMULSION AS AN INTRAVESICAL MEDIUM TO DISPERSE LIGHT IN THE POTENTIAL TREATMENT OF BLADDER-TUMORS [J].
BAGHDASSARIAN, R ;
WRIGHT, MW ;
VAUGHN, SA ;
BERNS, MW ;
MARTIN, DC ;
WILE, AG .
JOURNAL OF UROLOGY, 1985, 133 (01) :126-130
[4]   MESO-TETRA(HYDROXYPHENYL)PORPHYRINS, A NEW CLASS OF POTENT TUMOR PHOTOSENSITIZERS WITH FAVORABLE SELECTIVITY [J].
BERENBAUM, MC ;
AKANDE, SL ;
BONNETT, R ;
KAUR, H ;
IOANNOU, S ;
WHITE, RD ;
WINFIELD, UJ .
BRITISH JOURNAL OF CANCER, 1986, 54 (05) :717-725
[5]   PHOTODYNAMIC THERAPY WITH PORPHYRIN AND PHTHALOCYANINE SENSITIZATION - QUANTITATIVE STUDIES IN NORMAL RAT-LIVER [J].
BOWN, SG ;
TRALAU, CJ ;
SMITH, PDC ;
AKDEMIR, D ;
WIEMAN, TJ .
BRITISH JOURNAL OF CANCER, 1986, 54 (01) :43-52
[6]   NOVEL RED ABSORBING BENZO[A]PHENOXAZINIUM AND BENZO[A]PHENOTHIAZINIUM PHOTOSENSITIZERS - INVITRO EVALUATION [J].
CINCOTTA, L ;
FOLEY, JW ;
CINCOTTA, AH .
PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1987, 46 (05) :751-758
[7]  
DARZYNKIEWICZ Z, 1988, CANCER RES, V48, P1295
[8]  
Department of Health and Social Security, GUID SAF US LAS MED
[9]  
Fowler GJS, 1988, LASERS MED SCI JUL
[10]  
GILL WB, 1984, CANCER, V53, P2724, DOI 10.1002/1097-0142(19840615)53:12<2724::AID-CNCR2820531230>3.0.CO