FORMULATION AND INVITRO-INVIVO CHARACTERIZATION OF SOLID DISPERSIONS OF PIROXICAM

被引：14

作者：

BHATTACHARYYA, M

BASU, SK

GUPTA, BK

GHOSAL, SK

MANDAL, SC

CHATTARAJ, SC

机构：

[1] Division of Pharmaceutics, Dept. of Pharmaceutical Technology, Jadavpur University, Calcutta

来源：

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY | 1993年 / 19卷 / 06期

关键词：

D O I：

10.3109/03639049309062979

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The present work embodies studies performed with solid dispersions of the non-steroidal anti-inflammatory agent piroxicam, using biocompatible water soluble polymers polyethylene glycol (PEG) 4000 and 6000 alone, as well as in blends of various proportions. Different physicochemical properties and in vitro characterization were carried out. In vivo studies were performed to correlate with in vitro studies.

引用

页码：739 / 747

页数：9

共 41 条

[1]

ANASTASIADON, 1984, DRUG DEV IND PHARM, V9, P103

[2]

ATKINSON R. M., 1962, ANTIBIOT AND CHEMOTHER, V12, P232

[3] PIROXICAM - A REAPPRAISAL OF ITS PHARMACOLOGY AND THERAPEUTIC EFFICACY [J].