COLLOID-CHEMICAL ASPECTS OF SLURRY PACKING TECHNIQUES IN MICROCOLUMN LIQUID-CHROMATOGRAPHY

被引：48

作者：

VISSERS, JPC ^{[1
]}

CLAESSENS, HA ^{[1
]}

LAVEN, J ^{[1
]}

CRAMERS, CA ^{[1
]}

机构：

[1] EINDHOVEN UNIV TECHNOL,COLLOID CHEM LAB,5600 MB EINDHOVEN,NETHERLANDS

来源：

ANALYTICAL CHEMISTRY | 1995年 / 67卷 / 13期

关键词：

D O I：

10.1021/ac00109a032

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The relationship between the coagulating properties of slurry suspensions, type of packing liquids, and final performance of slurry-packed microcolumns for liquid chromatography (LC) was investigated. The colloidal stability of stationary-phase suspensions was examined by means of sedimentation and g-potential experiments, Expressions for the theoretical sedimentation rate of noncoagulated particle suspensions were derived for spherical particles with completely and incompletely filled pores and for irregularly shaped particles with incompletely filled pores. The performance of the slurry-packed microcolumns was predominantly determined by the selection of the packing liquid. It is shown that the packing liquid preferably has to be coagulating to obtain efficient and stable packed capillary LC columns. The selection of the slurry liquid on the column performance was of minor importance.

引用

页码：2103 / 2109

页数：7

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