ENANTIOSELECTIVE SYNTHESIS OF BETA-AMINO ACIDS .6. HIGH 1,2-STEREOINDUCTION IN THE PREPARATION OF ENANTIOPURE 2(R)-HYDROXY-3(R)-N-BENZOYLAMINO-3-PHENYLPROPIONIC ACID (LIKE STEREOISOMER OF TAXOLS SIDE-CHAIN)

被引：28

作者：

ESCALANTE, J ^{[1
]}

JUARISTI, E ^{[1
]}

机构：

[1] INST POLITECN NACL,CTR INVEST & ESTUDIOS AVANZADOS,DEPT QUIM,MEXICO CITY 07000,DF,MEXICO

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 25期

关键词：

D O I：

10.1016/0040-4039(95)00859-B

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The remarkably high 1,2-stereoinduction encountered in the hydroxylation of 1-benzoyl-3-methyl-6(S)-phenylperhydropyrimidin-4-one [(S)-2] allows for the preparation of enantiopure N-benzoyl (2R,3R)-3-phenylisoserine, the like stereoisomer of taxol's C-13 side chain.

引用

页码：4397 / 4400

页数：4

共 23 条

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[8] SYNTHESIS OF BIOLOGICALLY-ACTIVE TAXOL ANALOGS WITH MODIFIED PHENYLISOSERINE SIDE-CHAINS
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[9] A PRACTICAL CHEMOENZYMATIC SYNTHESIS OF THE TAXOL C-13 SIDE-CHAIN N-BENZOYL-(2R,3S)-3-PHENYLISOSERINE
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[10] HIGHLY SELECTIVE AND OPERATIONALLY SIMPLE SYNTHESIS OF ENANTIOMERICALLY PURE BETA-AMINO ESTERS VIA DOUBLE STEREODIFFERENTIATION
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