REDUCTIVE SILYLATION OF BENZOATES - CONVENIENT SYNTHESIS OF AROYLSILANES

被引：60

作者：

PICARD, JP ^{[1
]}

CALAS, R ^{[1
]}

DUNOGUES, J ^{[1
]}

DUFFAUT, N ^{[1
]}

GERVAL, J ^{[1
]}

LAPOUYADE, P ^{[1
]}

机构：

[1] UNIV BORDEAUX 1,FAC SCI,CNRS,COMPOSES ORGAN SILICIUM & ETAIN LAB,F-33405 TALENCE,FRANCE

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1979年 / 44卷 / 03期

关键词：

D O I：

10.1021/jo01317a024

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reductive silylation of benzoates ∑-C6H4COOR (1) by means of trimethylchlorosilane/magnesium/hexamethyl-phosphorictriamide affords a very convenient synthesis of a wide variety of aroyltrimethylsilanes ∑-C6H4C(O)-SiMe3 (3). through the formation of the corresponding ketals 2 which can be isolated. Scope and limitations of this new synthesis have been studied. The intermediate ketals undergo an unusual quantitative isomerization in the presence of base and/or heat, yielding substituted disiloxanes 8. © 1979, American Chemical Society. All rights reserved.

引用

页码：420 / 424

页数：5

共 20 条

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