ANTIBODIES SPECIFIC FOR FUSICOCCINS

Antibodies against fusicoccin (FC) were prepared by immunisation of rabbits with a conjugate of periodate-oxidised dideacetyl-FC and bovine serum albumin (BSA). Their specificities were investigated by hapten inhibition in an indirect haemagglutination test, assaying several derivatives and analogues of FC. The D-glucose moiety was not involved in the binding; conversely the interaction was severely impaired when the part of the molecule more remote from the sugar moiety was modified. In particular the cotylenins, which share with FCs most of the biological and chemical properties, did not react with the antibodies. © 1979.