A HOMOLOGY DOMAIN SHARED BETWEEN DROSOPHILA-OPTOMOTOR-BLIND AND MOUSE BRACHYURY IS INVOLVED IN DNA-BINDING

被引：93

作者：

PFLUGFELDER, GO ^{[1
]}

ROTH, H ^{[1
]}

POECK, B ^{[1
]}

机构：

[1] UNIV CALIF LOS ANGELES,DEPT BIOL CHEM,LOS ANGELES,CA 90024

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1992年 / 186卷 / 02期

关键词：

D O I：

10.1016/0006-291X(92)90833-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The distribution of sequence elements divides the optomotor-blind protein into three regions and is suggestive of a transcriptional regulatory role of this protein. The central region of Omb is homologous to the N-terminal half of the Brachyury protein. The conserved domain of Omb is here shown to possess general DNA binding affinity but has no significant similarity to recognized DNA binding motifs. © 1992.

引用

页码：918 / 925

页数：8

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