NEW ALUMINA-BASED STATIONARY PHASES FOR HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY - SYNTHESIS BY OLEFIN HYDROSILATION ON A SILICON HYDRIDE-MODIFIED ALUMINA INTERMEDIATE

A silanization procedure is used to form a layer of silicon hydride on the surface of alumina. IR and NMR data confirm the presence of the hydride on the surface. Modification of the hydride intermediate is accomplished by reaction with a terminal olefin in the presence of a transition metal catalyst to form an alkyl-bonded material. Both IR and NMR confirm the bonding of the alkyl ligand to the hydride surface. Chromatographic tests indicate reversed-phase behavior. Exposure to high concentrations of phosphate solution for an extended period resulted in no significant deterioration of the bonded phase.