THERMAL-STABILITY SCREENING AND REACTION CALORIMETRY - APPLICATION TO RUNAWAY REACTION HAZARD ASSESSMENT AND PROCESS SAFETY MANAGEMENT

This paper describes a methodology for runaway reaction hazard assessment and process safety management in this field. This methodology includes: a preliminary hazard assessment method based on information from the literature a testing methodology to determine the product thermal stability as well as the relevant kinetic and pressure information a method of process safety analysis devoted to runaway reaction hazard, including homogeneous and heterogeneous situations as well as Arrhenius and non-Arrhenius reactions recommendations for prevention and mitigation measures, based on process situations and on the experimental information obtained This methodology should be applied to any complex situation for the control of runaway reaction hazard