THE ACTION OF THE PROTEIN KINASE-C INHIBITOR, STAUROSPORINE, ON HUMAN-PLATELETS - EVIDENCE AGAINST A REGULATORY ROLE FOR PROTEIN KINASE-C IN THE FORMATION OF INOSITOL TRISPHOSPHATE BY THROMBIN

被引：244

作者：

WATSON, SP ^{[1
]}

MCNALLY, J ^{[1
]}

SHIPMAN, LJ ^{[1
]}

GODFREY, PP ^{[1
]}

机构：

[1] RADCLIFFE INFIRM,DEPT CLIN PHARMACOL,OXFORD OX2 6HE,ENGLAND

来源：

BIOCHEMICAL JOURNAL | 1988年 / 249卷 / 02期

基金：

英国惠康基金;

关键词：

D O I：

10.1042/bj2490345

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：345 / 350

页数：6

共 37 条

[1] LITHIUM AMPLIFIES AGONIST-DEPENDENT PHOSPHATIDYLINOSITOL RESPONSES IN BRAIN AND SALIVARY-GLANDS
BERRIDGE, MJ
DOWNES, CP
HANLEY, MR
[J]. BIOCHEMICAL JOURNAL, 1982, 206 (03) : 587 - 595
[2] BRASS LF, 1985, J BIOL CHEM, V260, P5172
[3] PROTEIN-KINASE-C PHOSPHORYLATES HUMAN-PLATELET INOSITOL TRISPHOSPHATE 5'-PHOSPHOMONOESTERASE, INCREASING THE PHOSPHATASE-ACTIVITY
CONNOLLY, TM
LAWING, WJ
MAJERUS, PW
[J]. CELL, 1986, 46 (06) : 951 - 958
[4] MULTIPLE, DISTINCT FORMS OF BOVINE AND HUMAN PROTEIN-KINASE-C SUGGEST DIVERSITY IN CELLULAR SIGNALING PATHWAYS
COUSSENS, L
PARKER, PJ
RHEE, L
YANGFENG, TL
CHEN, E
WATERFIELD, MD
FRANCKE, U
ULLRICH, A
[J]. SCIENCE, 1986, 233 (4766) : 859 - 866
[5] ROLE OF PROTEIN-KINASES IN STIMULATION OF HUMAN POLYMORPHONUCLEAR LEUKOCYTE OXIDATIVE-METABOLISM BY VARIOUS AGONISTS - DIFFERENTIAL-EFFECTS OF A NOVEL PROTEIN-KINASE INHIBITOR
GERARD, C
MCPHAIL, LC
MARFAT, A
STIMLERGERARD, NP
BASS, DA
MCCALL, CE
[J]. JOURNAL OF CLINICAL INVESTIGATION, 1986, 77 (01) : 61 - 65
[6] POTENTIATION BY THROMBIN OF THE SECRETION OF SEROTONIN FROM PERMEABILIZED PLATELETS EQUILIBRATED WITH CA2+ BUFFERS - RELATIONSHIP TO PROTEIN-PHOSPHORYLATION AND DIACYLGLYCEROL FORMATION
HASLAM, RJ
DAVIDSON, MML
[J]. BIOCHEMICAL JOURNAL, 1984, 222 (02) : 351 - 361
[7] INHIBITION OF PROTEIN-KINASE-C MEDIATED SIGNAL TRANSDUCTION BY TAMOXIFEN - IMPORTANCE FOR ANTITUMOR-ACTIVITY
HORGAN, K
COOKE, E
HALLETT, MB
MANSEL, RE
[J]. BIOCHEMICAL PHARMACOLOGY, 1986, 35 (24) : 4463 - 4465
[8] THROMBIN-INDUCED PHOSPHOINOSITIDE HYDROLYSIS IN PLATELETS - RECEPTOR OCCUPANCY AND DESENSITIZATION
HUANG, EM
DETWILER, TC
[J]. BIOCHEMICAL JOURNAL, 1987, 242 (01) : 11 - 18
[9] IMAOKA T, 1983, J BIOL CHEM, V258, P1404
[10] INAGAKI M, 1984, J BIOL CHEM, V259, P4321

← 1 2 3 4 →