EXPRESSION AND TURNOVER OF ACYLPHOSPHATASE (MUSCULAR ISOENZYME) IN L6 MYOBLASTS DURING MYOGENESIS

被引：21

作者：

BERTI, A ^{[1
]}

DEGL'INNOCENTI, D ^{[1
]}

STEFANI, M ^{[1
]}

RAMPONI, G ^{[1
]}

机构：

[1] UNIV SIENA, DEPT MOLEC BIOL, I-53100 SIENNA, ITALY

来源：

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS | 1992年 / 294卷 / 01期

关键词：

D O I：

10.1016/0003-9861(92)90166-T

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Acylphosphatase (muscular isoenzyme) levels have been measured in L6J1 myoblasts either proliferating or differentiating into myotubes. Results indicated that the increase in enzyme levels during differentiation is very similar to that of creatine kinase, a specific muscular enzyme. The half-lives of acylphosphatase in myoblasts and myotubes were also determined; t 1 2 values of 3 h 30 min (myoblasts), and 2 h 18 min (myotubes) were found. These results indicate that acylphosphatase could be considered a short-lived muscle-specific protein and that its increase in myotubes must be accompanied by an activation of its breakdown. © 1992.

引用

页码：261 / 264

页数：4

共 23 条

[1]

ALLEN A, 1979, PHYSIOL CHEM PHYS M, V69, P55

[2]

Ballard F J, 1977, Essays Biochem, V13, P1

[3] EFFECT OF EXOGENOUSLY ADDED ACYLPHOSPHATASES ON INOSITOL LIPID-METABOLISM IN HUMAN-PLATELETS [J].