DYNORPHIN-(1-13) INDUCES SPONTANEOUS FEEDING IN RATS

被引：217

作者：

MORLEY, JE

LEVINE, AS

机构：

[1] VET ADM MED CTR, NEUROENDOCRINE RES LAB, MINNEAPOLIS, MN 55417 USA

[2] UNIV MINNESOTA, DEPT MED, ST PAUL, MN 55108 USA

[3] UNIV MINNESOTA, DEPT FOOD SCI & NUTR, ST PAUL, MN 55108 USA

来源：

LIFE SCIENCES | 1981年 / 29卷 / 18期

关键词：

D O I：

10.1016/0024-3205(81)90522-1

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Dynorphin-(1-13), a recently isolated opioid peptide stimulates food ingestion in rats after intracerebroventricular administration at doses of 1 and 10 .mu.g. The latency until food ingestion is 22.4 .+-. 1.9 min. The ability of dynorphin-(1-13) to initiate food ingestion is antagonized by the opiate antagonist, naloxone. The food ingestion is accompanied by excessive grooming behavior.

引用

页码：1901 / 1903

页数：3

共 21 条

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