RECEPTOR-MEDIATED UPTAKE OF LOW-DENSITY LIPOPROTEIN RECONSTITUTED WITH 25-HYDROXYCHOLESTERYL OLEATE SUPPRESSES 3-HYDROXY-3-METHYLGLUTARYL-COENZYME-A REDUCTASE AND INHIBITS GROWTH OF HUMAN FIBROBLASTS

被引：60

作者：

KRIEGER, M ^{[1
]}

GOLDSTEIN, JL ^{[1
]}

BROWN, MS ^{[1
]}

机构：

[1] UNIV TEXAS, HLTH SCI CTR, DEPT INTERNAL MED, DALLAS, TX 75235 USA

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1978年 / 75卷 / 10期

关键词：

D O I：

10.1073/pnas.75.10.5052

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：5052 / 5056

页数：5

共 17 条

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FAUST, JR ;

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[4] FAMILIAL HYPERCHOLESTEROLEMIA - DEFECTIVE BINDING OF LIPOPROTEINS TO CULTURED FIBROBLASTS ASSOCIATED WITH IMPAIRED REGULATION OF 3-HYDROXY-3-METHYLGLUTARYL COENZYME A REDUCTASE-ACTIVITY [J].

BROWN, MS ;

GOLDSTEIN, JL .

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GOLDSTEIN, JL .

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[7]

BROWN MS, 1974, J BIOL CHEM, V249, P7306

[8] I125 LABELED HUMAN EPIDERMAL GROWTH-FACTOR - BINDING, INTERNALIZATION, AND DEGRADATION IN HUMAN FIBROBLASTS [J].

CARPENTER, G ;

COHEN, S .

JOURNAL OF CELL BIOLOGY, 1976, 71 (01) :159-171

[9] INHIBITION OF CELL-GROWTH BY OXYGENATED DERIVATIVES OF CHOLESTEROL [J].

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[10]

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