BIOTRANSFORMATION OF 18-BETA-GLYCYRRHETINIC ACID BY CELL-SUSPENSION CULTURES OF GLYCYRRHIZA-GLABRA

被引：25

作者：

HAYASHI, H

FUKUI, H

TABATA, M

机构：

[1] Faculty of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto

来源：

PHYTOCHEMISTRY | 1990年 / 29卷 / 07期

关键词：

18β-glycyrrhetinic acid; biotransformation; glycosylation; Glycyrrhiza glabra; Leguminosae; plant cell culture;

D O I：

10.1016/0031-9422(90)83026-W

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Two biotransformation products formed from 18β-glycyrrhetinic acid by cell suspension cultures of Glycyrrhiza glabra were isolated and their structures determined by chemical and spectral data as 3-O-[α-l-arabinopyranosyl-(1→2)-β-d-Glucuronopyranosyl]-24-hydroxy-18β-glycyrrhetinic acid and 30-O-β-d-glycopyranosyl-18β-glycyrrhetinic acid. The formation of glycyrrhizin, the main triterpene glucuronide of the licorice root, was not detected among the biotransformation products. This is the first report of the glucuronylation of an exogenous triterpene in plant cell cultures. © 1990.

引用

页码：2149 / 2152

页数：4

共 8 条

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