DELAYED BRAIN-DAMAGE IN ADULT MONKEYS FROM RADIATION IN THE THERAPEUTIC RANGE

被引：29

作者：

WAKISAKA, S ^{[1
]}

ONEILL, RR ^{[1
]}

KEMPER, TL ^{[1
]}

VERRELLI, DM ^{[1
]}

CAVENESS, WF ^{[1
]}

机构：

[1] NINCDS,EXPTL NEUROL LAB,BETHESDA,MD 20205

来源：

RADIATION RESEARCH | 1979年 / 80卷 / 02期

关键词：

D O I：

10.2307/3575057

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Twenty-one adult Macaca mulatta that received 6000 rad of supervoltage X irradiation in 30 fractions, alternate sides of the brain being exposed on alternate days, showed widely scattered minute necrotic lesions in the forebrain white matter in one out of three monkeys at 33 weeks, two out of three at 52 weeks, and two out of three at 104 weeks. With passage of time there was an increasing number of lesions with a trend toward mineralization except for those that extended into the cerebral cortex. Accompanying the necrotic lesions were both focal vascular endothelial hyperplasia and patches of telangiectasis.

引用

页码：277 / 291

页数：15

共 21 条

[1] CHANGES IN THE CENTRAL NERVOUS SYSTEM FOLLOWING IRRADIATION WITH 23-MEV X-RAYS FROM THE BETATRON [J].