A COMPARISON BETWEEN EFFECTS OF SECRETIN AND HISTAMINE ON GASTRIC SECRETION OF PEPSIN IN MAN

被引:16
作者
BERSTAD, A
PETERSEN, H
机构
[1] Laboratory of Gastroenterology, Department IX, Ullevaal Hospital, Oslo
关键词
Gastric secretion; Histamine; Hydrochloric acid determination; Pepsin; Secretin;
D O I
10.3109/00365526909180642
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
The stimulating effect on the gastric secretion of pepsin of an intravenous injection of one clinical unit of pure secretion per kg body weight was compared to the effect of a subcutaneous injection of 50 μg histamine dihydrochloride per kg body weight in the same series of subjects. The pattern of the pepsin response differed markedly. The ratio between the amounts of pepsin and HCl secreted decreased after injection of histamine, whereas it increased after injection of secretin. The effect of secretin on the pepsin/HCl ratio lasted for about two hours. © 1969 Informa UK Ltd.
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页码:511 / &
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