DYNAMICS OF A CLASS OF IMMUNE NETWORKS .2. OSCILLATORY ACTIVITY OF CELLULAR AND HUMORAL COMPONENTS

被引：42

作者：

STEWART, J ^{[1
]}

VARELA, FJ ^{[1
]}

机构：

[1] ECOLE POLYTECH,CREA,F-75230 PARIS 05,FRANCE

来源：

JOURNAL OF THEORETICAL BIOLOGY | 1990年 / 144卷 / 01期

关键词：

D O I：

10.1016/S0022-5193(05)80302-9

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Simulations show that for a certain range of its free parameters, a model of the immune network including both cellular and humoral components is capable of self-sustained oscillations. The model also possesses a number of fixed points which appear to be unstable. These results, taken together, suggest the hypothesis that the immune network may be able to sustain a non-degenerate diversity of active clones which are actively connected to each other only on condition that the activities of these clones are oscillatory. © 1990 Academic Press Limited All rights reserved.

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页码：103 / 115

页数：13

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