CHRONIC PERSISTENT COUGH - USE OF IPRATROPIUM BROMIDE IN UNDIAGNOSED CASES FOLLOWING UPPER RESPIRATORY-TRACT INFECTION

被引：40

作者：

HOLMES, PW ^{[1
]}

BARTER, CE ^{[1
]}

PIERCE, RJ ^{[1
]}

机构：

[1] MONASH MED CTR,DEPT RESP MED,CLAYTON,VIC,AUSTRALIA

来源：

RESPIRATORY MEDICINE | 1992年 / 86卷 / 05期

关键词：

D O I：

10.1016/S0954-6111(06)80010-7

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The clinical effects of inhaled ipratropium bromide were studied in 14 non-smoking patients with persistent post-viral infective cough employing a controlled double-blind, cross-over trial. Patients were selected if they demonstrated no apparent underlying cause for their persistent cough after appropriate radiological and respiratory function tests including methacholine reactivity and bronchoscopic examination. Inhaled ipratropium bromide (320 μg day−1) produced significantly less day and night time cough (P<0·05) with overall clinical improvement in 12 cases, five of whom had total resolution of their cough. We conclude that ipratropium bromide is an effective treatment in non-smoking adults with protracted cough following clinical upper respiratory tractinfection. © 1992, Baillière Tindall. All rights reserved.

引用

页码：425 / 429

页数：5

共 13 条

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[2]

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[3]

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[4]

EMPEY DW, 1976, AM REV RESPIR DIS, V113, P131