TET DETERMINANTS PROVIDE POOR PROTECTION AGAINST SOME TETRACYCLINES - FURTHER EVIDENCE FOR DIVISION OF TETRACYCLINES INTO 2 CLASSES

被引：30

作者：

OLIVA, B ^{[1
]}

CHOPRA, I ^{[1
]}

机构：

[1] AMER CYANAMID CO,LEDERLE LABS,INFECT DIS RES SECT,DEPT MICROBIAL BIOCHEM & GENET,PEARL RIVER,NY 10965

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1992年 / 36卷 / 04期

关键词：

D O I：

10.1128/AAC.36.4.876

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Atypical tetracyclines were active against Escherichia coli and Staphylococcus aureus strains containing determinants that mediate resistance to typical tetracyclines by efflux (Tet B and Tet K) or ribosomal protection (Tet M) mechanisms. The results support recently published data that tetracyclines are divisible into at least two classes on the basis of their modes of action.

引用

页码：876 / 878

页数：3

共 15 条

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