PENNERS SEROTYPE-4 OF CAMPYLOBACTER-JEJUNI HAS A LIPOPOLYSACCHARIDE THAT BEARS A GM1 GANGLIOSIDE EPITOPE AS WELL AS ONE THAT BEARS A GD1A EPITOPE

被引：88

作者：

YUKI, N

TAKI, T

TAKAHASHI, M

SAITO, K

TAI, T

MIYATAKE, T

HANDA, S

机构：

[1] TOKYO MED & DENT UNIV,FAC MED,DEPT NEUROL,TOKYO 113,JAPAN

[2] TOKYO METROPOLITAN INST MED SCI,DEPT TUMOR IMMUNOL,BUNKYO KU,TOKYO 113,JAPAN

[3] TOKYO METROPOLITAN RES LAB PUBL HLTH,DEPT MICROBIOL,SHINJUKU KU,TOKYO,JAPAN

来源：

INFECTION AND IMMUNITY | 1994年 / 62卷 / 05期

关键词：

D O I：

10.1128/IAI.62.5.2101-2103.1994

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The carbohydrate structures of lipopolysaccharides (LPSs) of Campylobacter jejuni strains belonging to Penner's serotypes (PEN) 1, 2, 4, 19, 23, and 36 were studied by thin-layer chromatography and immuno-staining with several monoclonal antiganglioside antibodies. Auti-GM1 and anti-GD1a antibodies reacted with the LPSs of PEN 1, 4, and 19. Aspinall et al. (G. O. Aspinall; A. G. McDonald, T. S. Raju, H. Pang, A. P. Moran, and J. L. Penner. Eur. J. Biochem. 213:1017-1027, 1993) recently reported that the LPS of PEN 4 has a GD1a ganglioside-like structure rather than a GM1-like structure. We found that the LPS fraction of C.jejuni (PEN 4) has an LPS that bears a GM1 epitope as well as an LPS that bears a GD1a epitope.

引用

页码：2101 / 2103

页数：3

共 25 条

[1] CHEMICAL-STRUCTURE OF THE CORE REGION OF CAMPYLOBACTER-JEJUNI SEROTYPE O-2 LIPOPOLYSACCHARIDE [J].