COMPARATIVE INVITRO ACTIVITY OF CEFIXIME AGAINST HAEMOPHILUS-INFLUENZAE ISOLATES, INCLUDING AMPICILLIN-RESISTANT, NON-BETA-LACTAMASE-PRODUCING ISOLATES, FROM PEDIATRIC-PATIENTS
The in vitro activity of cefixime was comparatively tested against 232 non-type b and 102 type b isolates of Haemophilus influenzae derived from clinical specimens of pediatric patients, including 10 non-type b strains that did not produce β-lactamase and demonstrated resistance to ampicillin. Cefixime was active against the ampicillin-susceptible and ampicillin-resistant, β-lactamase-producing isolates; however, its activity against some non-β-lactamase-producing, ampicillin-resistant isolates appeared to be limited.